Waynesboro is a medium-sized borough located in the state of Pennsylvania. With a population of 11,067 people and five associated neighborhoods, Waynesboro is the 95th largest community in Pennsylvania. Much of the housing stock in Waynesboro was built prior to World War II, making it one of the older and more historic boroughs in the country.

Being a small borough, Waynesboro does not have a public transit system used by locals to get to and from work.

The percentage of adults in Waynesboro with college degrees is slightly lower than the national average of 21.84% for all communities. 13.31% of adults in Waynesboro have a bachelor's degree or advanced degree.

The per capita income in Waynesboro in 2022 was $27,339, which is lower middle income relative to Pennsylvania and the nation. This equates to an annual income of $109,356 for a family of four. However, Waynesboro contains both very wealthy and poor people as well.

Waynesboro is a somewhat ethnically-diverse borough. The people who call Waynesboro home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Waynesboro residents report their race to be White, followed by Black or African-American. Important ancestries of people in Waynesboro include German, Irish, English, Italian, and French.

The most common language spoken in Waynesboro is English. Other important languages spoken here include Spanish and German/Yiddish.